Nazivin contraindications. Nazivin - vasoconstrictor nasal drops for runny nose. Detailed description

Manufacturer: Merck Selbstmedikation (Merck Selbstmedikation) Germany

ATS code: R01AA05

Farm group:

Release form: Liquid dosage forms. Nasal drops.

General characteristics. Compound:

Active substance:
Nazivin 0.01% - Oxymetazoline hydrochloride 0.1 mg
Nazivin 0.025% - Oxymetazoline hydrochloride 0.25 mg
Nazivin 0.05% - Oxymetazoline hydrochloride 0.5 mg

Excipients: benzalkonium chloride 50% solution, disodium edetate dihydrate, sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dihydrate, sodium hydroxide 1 M solution, purified water.

Pharmacological properties:

Pharmacodynamics. Nazivin® (oxymetazoline) has vasoconstrictor effect. When applied topically to the inflamed nasal mucosa, it reduces swelling and nasal discharge. Restores nasal breathing.
Elimination of mucosal edema helps restore aeration paranasal sinuses nose, middle ear cavity, which prevents the development of bacterial complications (sinusitis, middle ear).
When used locally intranasally in therapeutic concentrations, it does not irritate the mucous membrane and does not cause hyperemia.
When administered locally intranasally, the drug does not have a systemic effect. The drug begins to act quickly (within a few minutes). The duration of action of Nazivin is up to 12 hours.

Indications for use:

Treatment of acute respiratory diseases accompanied by a runny nose;
-allergic rhinitis;
-vasomotor rhinitis;
- to restore drainage in case of inflammation of the paranasal sinuses, eustachitis, otitis media;
-to eliminate swelling before diagnostic manipulations in the nasal passages.

Important! Get to know the treatment

Directions for use and dosage:

Nazivin® 0.01%, 0.025% and 0.05% drops are intended for use in the nose.
Adults and children over 6 years of age: use Nazivin® 0.05% drops, 1 to 2 drops in each nasal passage 2-3 times a day.
Children from 1 year to 6 years: use Nazivin® 0.025% drops, 1 - 2 drops in each nasal passage 2-3 times a day.
Children under 1 year: Children under 4 weeks of age are prescribed 1 drop of Nazivin® 0.01% in each nasal passage 2-3 times a day. From the 5th week of life to 1 year - 1 - 2 drops in each nasal passage 2-3 times a day.
To ensure dosage accuracy, the bottle of Nazivin® 0.01% drops has a graduated pipette with markings on the number of drops. For example, if 1 drop is prescribed, then the pipette should be filled with the solution to the 1 mark.
The following procedure has also been proven effective: depending on age, 1-2 drops of a 0.01% solution are applied to cotton wool and wiped over the nasal passages. Nazivin® 0.01%, 0.025% and 0.05% drops should be used for 3 to 5 days. Doses higher than recommended can only be used under medical supervision.

Features of application:

Should be avoided long-term use and drug overdose, especially in children.

Impact on the ability to drive vehicles and equipment:
After long-term use or taking cold remedies containing oxymetazoline in doses higher than recommended cannot be ruled out overall impact on cardiovascular system and central nervous system. In these cases, the ability to manage vehicle or equipment may be reduced.

Side effects:

Sometimes: burning or dryness of the nasal membranes,. IN in rare cases: after the effect of using Nazivin® wears off, strong feeling"stuffy" nose (reactive hyperemia). Repeated overdose with local nasal use sometimes leads to such systemic sympathomimetic effects as increased heart rate (tachycardia) and increased blood pressure. In very rare cases, anxiety, insomnia, fatigue, headaches, etc. have been observed. Long continuous use vasoconstrictor drugs may lead to tachyphylaxis, nasal mucosa and recurrent swelling of the nasal mucosa ( drug-induced rhinitis).

Interaction with other drugs:

Interaction with other drugs
When MAO blockers and tricyclic antidepressants are prescribed simultaneously, blood pressure increases.
Co-administration of other vasoconstrictors medicines increases the risk of developing side effects.

Contraindications:

Atrophic rhinitis; closed angle; hypersensitivity to the components of the drug.
You should adhere to the recommended concentrations of the drug intended for different age categories(see methods of application).

Carefully
In patients taking monoamine oxidase inhibitors and other drugs that increase blood pressure for up to 10 days after their use; with increased intraocular pressure, during pregnancy and lactation, with severe forms cardiovascular diseases(hypertension, ); with thyrotoxicosis and diabetes mellitus.

Pregnancy and lactation
When used during pregnancy or breastfeeding Do not exceed the recommended dosage. The drug should be used only after a careful assessment of the risk-benefit ratio for the mother and fetus.

Overdose:

After a significant overdose or accidental ingestion, symptoms may appear. following symptoms: constriction of the pupils, nausea, cyanosis, fever, depression of cardiac activity, respiratory disorders. In addition, there may appear mental disorders, as well as depression of the functions of the central nervous system, accompanied by drowsiness, decreased body temperature, bradycardia, arterial hypotension, respiratory arrest and possible development coma. In case of overdose associated with oral administration of the drug, it is prescribed, Activated carbon.

Storage conditions:

Store at a temperature not exceeding 25 °C.
Keep out of the reach of children.

Vacation conditions:

Over the counter

Package:

Nasal drops 0.01%; 0.025% and 0.05%.
For Nazivin® 0.01%: 5 ml in a dark glass bottle with a pipette cap.
For Nazivin® 0.025% and 0.05%: 10 ml in a dark glass bottle with a pipette cap.
1 bottle with instructions for use is placed in a cardboard box.

The most common causes of a runny nose are various viruses, allergens, or pathogenic bacteria. They provoke inflammation of the mucous membrane and its swelling, copious discharge from the nose, interfere with breathing through the nose, eating and sleeping peacefully at night.

To combat such symptoms in children, they often use vasoconstrictor medications. One of the medications in this group is Nazivin. In what forms is it produced, how does it affect the child’s body, what dose is recommended in childhood and how to properly apply Nazivin to a child’s nose over a year old?

Release form and composition

The drug is produced in the form of almost clear liquid, which has no color or has little yellow tint. The main ingredient of this solution is oxymetazoline in the form of hydrochloride. The concentration of this substance varies, as does the packaging of the medicine. Nazivin is presented in pharmacies:

• Drops in the nose. They are available in glass bottles equipped with special pipettes on the cap. The concentration of such a drug can be 0.01%, 0.025% and 0.05%. The drug with the lowest dosage is intended for children under one year old and is presented in a 5 ml bottle. Drops with a concentration of 0.025% and 0.05% are available in 10 ml in one bottle. In addition to oxymetazoline, they contain disodium edetate, dihydrogen phosphate and sodium hydrogen phosphate, as well as water, sodium hydroxide and benzalkonium chloride.
• Nasal spray. It is produced in plastic bottles that have a sprayer. Inside one bottle there is 10 ml of solution, and the concentration of oxymetazoline in it is 0.05%, which corresponds to a dosage of 500 µg/1 ml. Additional components The medications are citric acid, glycerol, benzalkonium chloride, purified water and sodium citrate.

In addition, Nazivin Sensitive can be seen in the assortment of pharmacies. The main component of this medicine (oxymetazoline). Possible indications negative effects and the contraindications are completely the same as for regular Nazivin. First of all, the drug labeled “sensitive” is intended for children prone to allergies, since it does not include benzalkonium chloride and is less likely to cause an allergic reaction.

One of the forms of Nazivin Sensitive are drops that contain 0.01% of the active ingredient and are used in the treatment infants. For children older than one year, the medication is produced in the form of a dosed spray:

• With an active ingredient content of 11.25 mcg per dose, which corresponds to a concentration of 250 mcg/1 ml.
• Containing oxymetazoline in 1 dose in the amount of 22.5 mcg, that is, with a concentration of 500 mcg/1 ml.

Each of these medications is available in 10 ml bottles and contains approximately 220 doses of medication. The bottles are made of plastic and equipped with a special dispensing device.

Operating principle

The active compound Nazivin affects alpha-2 adrenergic receptors, resulting in a narrowing small vessels which are located in the nasal passages. Use of the medicine:

• Reduces swelling and hyperemia of the nasopharyngeal mucosa.
• Reduces the volume of nasal discharge.
• Helps restore breathing through the nose.
• Additionally, it affects the paranasal sinuses, as well as the middle ear, preventing complications of a runny nose in the form of sinusitis or otitis media.
• Renders therapeutic effect only at the processing site.
• Does not provoke redness and irritation of the mucous membrane inside the nasal passages.

The medication begins to act literally in the first minutes after it enters the nose, and vasoconstrictor effect after treatment with the solution lasts up to 12 hours.

Indications

In childhood, Nazivin is in demand:

• In the treatment of ARVI, if the disease manifests itself as a runny nose.
• In the treatment of allergic rhinitis.
• In the treatment of rhinitis, which is called vasomotor.
• In combination with other medications for eustachitis, adenoids, otitis media or sinusitis.
• Before performing any diagnostic manipulations in the nasal passages.

What forms are used for children over one year old?

For infants, 0.01% drops are produced, but for older children, the amount of active compound in this Nazivin will be insufficient. At the age of one to six, drops containing 0.025% oxymetazoline are prescribed. For the treatment of children over 6 years of age, a 0.05% solution in any form is prescribed.

As for Nazivin Sensitive, only a spray is used in children over one year of age, one dose of which contains 11.25 mcg of the active ingredient. A more concentrated product containing 22.5 mcg of oxymetazoline in each dose is used from the age of six.

What to choose?

Choosing the most optimal shape medications for a child, first of all, take into account the concentration of the drug, after which they are determined by the packaging. Let us note that it is very convenient to use both types of Nazivin - the drops are easily dosed and fall directly into the baby’s nose thanks to the curved shape of the pipette built into the lid, and the spray is sprayed with a light pressure over the entire mucous membrane in the required dose. However, in practice, the spray form seems more suitable to most mothers, since you do not need to lie down to administer the drug, and the risk of overdose with such a drug is minimal.

Contraindications

Treatment with Nazivin is prohibited:

• If you are hypersensitive to oxymetazoline or another ingredient of the solution.
• For angle-closure glaucoma.
• With rhinitis occurring in an atrophic form.

If a child has any diseases of the cardiovascular system, diabetes mellitus is detected, or there is thyrotoxicosis, Nazivin should be dripped or injected with caution.

Side effects

TO side effects include:

• Sometimes after administration of Nazivin into the nose such negative symptoms occur local symptoms, such as a feeling of dryness, sneezing, slight burning, discomfort in the nasal passages.
• After the cessation of action, reactive hyperemia is often observed and the child begins to complain of nasal congestion.
• In some children, the drug provokes restless behavior, nausea, sleep disturbances, fatigue, and headaches.
• Long-term use of the solution/drops causes addiction and medicinal rhinitis. In addition, very long treatment capable of causing atrophic changes nasal mucosa.

Instructions for use

Before injecting/dropping Nazivin, you should clean the nasal passages, removing excess secretions from them. To do this, it is advised to use a syringe or aspirator, because the use cotton swabs may be dangerous, especially in early age. Little patient Before using the drops, place them on a flat surface and tilt the head slightly. An older child is asked to sit down and tilt his head back slightly. The medication is first dripped into one nasal passage so that the drug reaches the side wall, and then repeat the same steps for the second nostril.

If a spray is used, the child should be warned to hold his breath. After finishing the procedure, wipe off the excess solution that has flowed out of the nose with a cotton pad or napkin.

For patients from 1 to 6 years of age, the solution is prescribed in the following single doses:

• One or two drops of 0.025% Nazivin in the form of nasal drops.
• One injection of Sensitive spray containing 11.25 mcg of oxymetazoline in each dose.

If the child is already 6 years old, then use the following single dosages:

• One drop of Nazivin 0.05%, produced in nasal drops (sometimes 2 drops at once).
• 1 injection of 0.05% Nazivin spray.
• One injection of the drug Sensitive containing 22.5 mcg of active compound in each dose.

Overdose

Due to an excessive dose of Nazivin, vomiting, constriction of the pupils, increased heart rate, respiratory failure, fever, arrhythmia and other symptoms appear. If the overdose is severe, pulmonary edema, mental disorders and even coma may occur. Having discovered poisoning, after lavaging the stomach, you must immediately call an ambulance.

Interaction with other drugs

Like many other vasoconstrictor medications, Nazivin cannot be used with MAO blockers or tricyclic antidepressants. Also, you should not inject any other means that constrict blood vessels (for example, Otrivin or Xylene) into the nasal passages along with Nazivin, as this will increase the side effects of the drops or spray.

Terms of sale

All forms of Nazivin are classified as over-the-counter medications, so you can easily purchase the medicine at most pharmacies. The price of the drug depends on its form and concentration, for example, 0.05% Nazivin spray costs an average of 140 rubles, and for 10 ml of 0.025% drops you need to pay from 130 to 150 rubles. Sensitive medications are slightly more expensive - 160-180 rubles per bottle.

Storage conditions and shelf life

It is recommended to keep Nazivin and Nazivin Sensitive at home at temperatures up to 25 degrees Celsius in a place where the medication will be securely hidden from small children. The shelf life of all forms of the medicine is 3 years. If it has expired, dripping or squirting the solution into the child’s nose is unacceptable. The date after which the medicine is no longer used is marked on the packaging of the spray or drops and does not depend on the time of opening.

Nazivin– a drug in the form of nasal drops or spray, which has a pronounced anti-edematous and vasoconstrictor effect. The composition of the drug includes active ingredient– oxymetazoline – stimulating alpha-adrenergic receptors located in the smooth muscle layer of the vessels of the nasal mucosa. The drug eliminates rhinorrhea, swelling of the nasal mucosa and paranasal sinuses, and facilitates nasal breathing. When using the drug in therapeutic doses no stimulation of alpha1-adrenergic receptors was noted, however, when using high doses, oxymetazoline may have some effect on alpha1-adrenergic receptors.

The drug is not absorbed into systemic blood flow and does not have a systemic effect.

Indications for use

The drug is used to treat patients with acute rhinitis of various etiologies, including allergic rhinitis.

The drug is prescribed to patients with vasomotor rhinitis, sinusitis, inflammation eustachian tube and middle ear, as well as in acute respiratory diseases, which are accompanied by impaired nasal breathing.

In addition, the drug can be prescribed in preparation for various diagnostic procedures.

Mode of application

Nazivin 0.05% (nasal drops, spray):

Adults and children over 6 years of age are usually prescribed 1-2 drops (1-2 injections) of the drug 2-3 times a day.

Nazivin 0.025% (nasal drops):

Children aged 1 to 6 years are usually prescribed 1-2 drops of the drug 2-3 times a day.

Nazivin 0.01% (nasal drops):

Children aged from birth to 4 weeks are usually prescribed 1 drop of the drug 2-3 times a day.

Children aged 5 weeks to 1 year are usually prescribed 1-2 drops of the drug 2-3 times a day.

In addition to instilling the drug into the nasal passages, it is also possible to apply required amount of the drug (1-2 drops) on a cotton swab and treat the nasal passages.

It should be taken into account that with long-term use of the drug its therapeutic effect decreases slightly.

Side effects

The drug is usually well tolerated by patients; in isolated cases, a burning sensation and dryness of the nasal mucosa, reactive hyperemia, and sneezing were noted.

When using excessive doses of the drug for a long time, the development of tachycardia, arterial hypertension, disturbances in sleep and wakefulness, headache and nausea is possible.

Contraindications

Increased individual sensitivity to the components of the drug.

The drug is contraindicated in patients suffering from angle-closure glaucoma.

The drug is not used for the treatment of patients suffering from atrophic rhinitis.

A drug Nazivin 0.05% is contraindicated for children under 6 years of age, Nazivin 0.025% for children under 1 year of age.

Caution should be exercised when prescribing the drug to patients with arterial hypertension, tachycardia, atherosclerosis, diabetes mellitus, hyperthyroidism, as well as increased intraocular pressure and pheochromocytoma.

Pregnancy

The drug can be used during pregnancy as prescribed by the attending physician, who must carefully weigh the expected benefits for the mother and potential risks for the fetus.

If it is necessary to use the drug during lactation, minimal doses should be used. effective doses oxymetazoline.

Interaction with other drugs

When the drug is used in combination with monoamine oxidase inhibitors and tricyclic antidepressants, the development of arterial hypertension is possible.

Overdose

When using excessive doses of the drug, as well as in case of accidental orally the drug may develop nausea, vomiting, increased body temperature, disorders heart rate, arterial hypertension, respiratory disorders, pulmonary edema and cardiac arrest. In addition, some patients experienced depression of the functions of the central nervous system and the development of drowsiness, arterial hypotension, bradycardia, respiratory arrest and coma.

There is no specific antidote. In case of accidental oral administration of the drug, gastric lavage and enterosorbents are indicated. In case of overdose, symptomatic therapy is carried out.

Release form

Nasal drops, 10 ml in a bottle, 1 bottle in a cardboard box.

Today pharmacies are simply overcrowded various compositions to help relieve nasal congestion in children. But it’s not so easy to choose, because you need to drip drops, taking into account individual characteristics child's body and the course of the disease. The best option today remains Nazivin. We will consider the properties of this drug in the article.

Effect

The presented medication contains oxymetazoline. Thanks to this, Nazivin has a vasoconstrictor effect. By using the medicine topically, it is possible to reduce inflammatory process the nasal mucosa, removing swelling and discharge from the nasal cavity. If you follow the instructions and dosage, you can restore nasal breathing.

Restoring aeration of the paranasal sinuses helps eliminate swelling, as well as protect against the development of bacterial complications. The most dangerous are sinusitis, sinusitis and otitis media.

If you use the drug topically in the dosages indicated in the instructions, the mucous membrane will not be irritated, and there will be no redness.

In addition, Nazivin does not have a systemic effect. The positive effect is noticeable after just a few minutes. The resulting effect will last for 12 hours.

Read how to use Nazivin correctly for newborns.

Required dosage and rules of use Nazivin should only be used topically in the nose. Thanks to unique composition

and safe effects, the medicine can be prescribed not only to adults, but also to children.

For babies up to one year old

For patients under 4 weeks of age, the drug should be used 1 drop in each nasal passage 3 times a day. When the baby is from 5 weeks to a year, you can drop 1-2 drops into each nostril 3 times a day.

From year

If the child is already one year old, then Nazivin should be used in the amount of 1-2 drops 3 times a day.

How many days to drip The question always arises for how many days can a child receive Nazivin drips. To comply exact dosage

The medicine used has a graduated pipette on which the number of drops is marked. If the child’s age corresponds to 1 drop, then take the medicine up to the 1 mark. Treatment with Nazivin is necessary for 3-5 days. In this case, it is necessary to strictly adhere to the dosage indicated above. If you use the drops for longer than the specified period, then addiction occurs and you will get

positive influence

This form of the drug can be used to treat runny nose in patients who have not yet reached one year of age. If your baby is not yet 4 weeks old, then you need to use one spray in each nostril 2-3 times a day. From 5 weeks to one year of age, apply 2 sprays 2-3 times a day.

Price

You can purchase a drug that relieves nasal congestion at any pharmacy without a prescription. Costs children's Nazivin only 165 rubles.

Reviews

• Margarita, 34 years old: “When the child had a runny nose, I immediately began to wash her nose saline solution. But he only allowed him to quickly remove the mucus, but only Nazivin was able to cope with nasal congestion. I used the drug for only 3 days and this unpleasant symptom"The runny nose disappeared."
• Elena, 25 years old:“I have been using Nazivin for a long time to treat my daughter’s runny nose. During all this time, we did not experience any side effects. Although my friend's situation is the opposite. When they used the drug, her son had a severe headache and a burning sensation.”
• Veronica, 45 years old: “Nazivin for children copes well with my grandson’s nasal congestion. He is 5 years old, but trips to the garden in the cold season always end with him getting sick. I tried many drops: Pinosol, Otrivin, but we were unable to get the same effect as from Nazivin. All we have to do is drip the child’s nose for 3-4 days, and the cold immediately goes away.”

Comparison with other drugs

With Nazol

The drug is produced specifically for the treatment of runny nose in young patients. With this treatment, it is possible to very quickly eliminate a runny nose, the cause of which is allergies, colds or viruses. If Nazivin does not help with a stuffy nose in a child, then you can try this remedy.

Nazol is a nasal drug that has a mild vasoconstrictor effect.

If we talk about Nazivin, it also has a vasoconstrictor effect, but also actively fights swelling of the nasal mucosa, making breathing easier. The main component is oxymetazoline hydrochloride. It is he who relieves swelling of the mucous membrane, and also, unlike Nazol, effectively removes accumulated mucus. Children will have to decide for themselves which is better to instill Nazol or Nazivin.

With Vibrocil

Let us first consider Vibrocillus. This spray is very effective and quickly relieves nasal congestion. Vibrocil can be used in the form of drops for newborns and in the form of a spray for older children. For elimination baby runny nose This medication is considered the most optimal. It should not be used by children who are prone to allergies. Answer the question what better than vibrocil or Nazivin for children will only be possible after trying both remedies.

The spray can be used for any colds.

Nazivin affects very quickly and strongly, powerfully affecting the delicate mucous membrane of the nose. If you choose between these two drugs, you should be guided by the age of the baby.

With Otrivin

Nazivin, unlike Otrivin, contains a smaller percentage of the main component. For this reason, Nazivin has a safe effect on children, but this does not affect its effectiveness in any way.

The medicine can be purchased at a pharmacy at a price of 190 rubles.

What to do if the remedy does not help

As noted earlier, the duration of treatment with the presented remedy should not exceed 5 days. If relief does not occur during this period, then you should consult a doctor. After examining the child, he will be able to draw a conclusion about the advisability of further use of Nazivin or prescribing another drug. In this case, you should not make independent decisions, otherwise you can harm the baby.

What happens if an adult drug is instilled into a child?

It is not recommended to use adult Nazivin for the treatment of children's runny nose, but if such a situation exists, then before use it is necessary to dilute the drops with purified water in a 1:1 ratio.

Cheap analogues

Analogues are great way save money cash and still get the desired result. The cheapest analogues of Nazivin include:

1. Nesopin - 84 rub.
2. Xylene - 28 rub.
3. Rinostop - 17 rub.
4. Rhinonorm - 89 rub.
5. For nose - 120 rub.
6. Nazol - 140 rub.
7. Fazin - 102 rub.

Video

This video will talk about the use of Nazivin and its analogues for the treatment of runny nose in children.

Nazivin is a drug for quick fix a child has a runny nose. The effectiveness of its use has been proven over the years and many mothers are satisfied with this treatment. If you strictly follow the instructions and do not exceed the duration of therapy, then the whole process treatment will pass quickly, and there will be no side effects. You will find a list of children's nasal drops for a runny nose.

Name of the drug: NAZIVIN ®

International nonproprietary name:

oxymetazoline

Dosage form:

nasal drops

Compound
1 ml of the drug contains:
Active substance:
Nazivin 0.01% - Oxymetazoline hydrochloride 0.1 mg
Nazivin 0.025% - Oxymetazoline hydrochloride 0.25 mg
Nazivin 0.05% - Oxymetazoline hydrochloride 0.5 mg
Excipients: benzalkonium chloride 50% solution, disodium edetate dihydrate, sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dihydrate, sodium hydroxide 1 M solution, purified water.

Description: Almost transparent, colorless to slightly yellowish color solution.

Pharmacotherapeutic group:

alpha 2 is an adrenomimetic agent.

ATX Code: .

Pharmacological properties

Pharmacodynamics. Nazivin ® (oxymetazoline) has a vasoconstrictor effect. When applied topically to the inflamed nasal mucosa, it reduces swelling and nasal discharge. Restores nasal breathing.
Elimination of mucosal edema helps restore aeration of the paranasal sinuses and middle ear cavity, which prevents the development of bacterial complications (sinusitis, sinusitis, otitis media).
When used locally intranasally in therapeutic concentrations, it does not irritate the mucous membrane and does not cause hyperemia.
When administered locally intranasally, the drug does not have a systemic effect. The drug begins to act quickly (within a few minutes). The duration of action of Nazivin is up to 12 hours.

Indications

treatment of acute respiratory diseases accompanied by a runny nose;

allergic rhinitis;

vasomotor rhinitis;

to restore drainage in case of inflammation of the paranasal sinuses, eustachitis, otitis media;

to eliminate swelling before diagnostic manipulations in the nasal passages. Contraindications
Atrophic rhinitis; angle-closure glaucoma; hypersensitivity to the components of the drug.
You should adhere to the recommended concentrations of the drug intended for different age categories (see methods of use). Carefully
In patients taking monoamine oxidase inhibitors and other drugs that increase blood pressure for up to 10 days after their use; with increased intraocular pressure, during pregnancy and lactation, with severe forms of cardiovascular diseases (hypertension, angina); with thyrotoxicosis and diabetes mellitus. Pregnancy and lactation
When used during pregnancy or breastfeeding, do not exceed the recommended dosage. The drug should be used only after a careful assessment of the risk-benefit ratio for the mother and fetus. Directions for use and doses
Nazivin ® 0.01%, 0.025% and 0.05% drops are intended for use in the nose.
Adults and children over 6 years of age: apply Nazivin ® drops 0.05% 1-2 drops in each nasal passage 2-3 times a day.
Children from 1 year to 6 years: apply Nazivin ® drops 0.025% 1 - 2 drops in each nasal passage 2-3 times a day.
Children under 1 year: Children under 4 weeks of age are prescribed 1 drop of Nazivin ® 0.01% in each nasal passage 2-3 times a day. From the 5th week of life to 1 year - 1 - 2 drops in each nasal passage 2-3 times a day.
To ensure dosage accuracy, the bottle of Nazivin ® 0.01% drops has a graduated pipette with markings on the number of drops. For example, if 1 drop is prescribed, then the pipette should be filled with the solution to the 1 mark.
The following procedure has also been proven effective: depending on age, 1-2 drops of a 0.01% solution are applied to cotton wool and wiped over the nasal passages. Nazivin ® 0.01%, 0.025% and 0.05% drops should be used for 3 to 5 days. Doses higher than recommended can only be used under medical supervision. special instructions
Long-term use and overdose of the drug should be avoided, especially in children. Interaction with other drugs
When MAO blockers and tricyclic antidepressants are prescribed simultaneously, blood pressure increases.
Co-administration of other vasoconstrictor drugs increases the risk of side effects. Side effect
Sometimes: burning or dryness of the nasal membranes, sneezing. In rare cases: after the effect of using Nazivin ® wears off, a strong feeling of “stuffiness” in the nose (reactive hyperemia). Repeated overdose with local nasal use sometimes leads to systemic sympathomimetic effects such as increased heart rate (tachycardia) and increased blood pressure. In very rare cases, anxiety, insomnia, fatigue, headaches and nausea have been observed. Long-term continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent swelling of the nasal mucosa (rhinitis medicamentosa). Overdose
After a significant overdose or accidental ingestion, the following symptoms may appear: constriction of the pupils, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, collapse, cardiac depression, arterial hypertension, pulmonary edema, respiratory disorders. In addition, mental disorders may appear, as well as depression of the functions of the central nervous system, accompanied by drowsiness, decreased body temperature, bradycardia, arterial hypotension, respiratory arrest and possible development of coma. In case of overdose associated with oral administration of the drug, gastric lavage and activated charcoal are prescribed. Impact on the ability to drive vehicles and equipment:
After long-term use or administration of cold remedies containing oxymetazoline in dosages exceeding the recommended ones, a general effect on the cardiovascular system and central nervous system cannot be excluded. In these cases, the ability to operate a vehicle or equipment may be impaired. Release form.
Nasal drops 0.01%; 0.025% and 0.05%.
For Nazivin ® 0.01%: 5 ml in a dark glass bottle with a pipette cap.
For Nazivin ® 0.025% and 0.05%: 10 ml in a dark glass bottle with a pipette cap.
1 bottle with instructions for use is placed in a cardboard box. Storage
Store at a temperature not exceeding 25 °C.
Keep out of the reach of children. Best before date
3 years.
Do not use after expiration date.

Conditions for dispensing from pharmacies:

over the counter.

Manufacturer:

Merck KGaA, Germany
Frankfurter str. 250, 64293 Darmstadt
Frankfurter str., 250,64293 Darmstadt Address of the representative office of Nycomed in Russia/CIS:
119049 Moscow, st. Shabolovka, 10, building 2.