Rare terrible diseases. The most terrible diseases that disfigure people
There are a huge number of different diseases in the world. But sometimes it’s an ordinary runny nose that goes away in a couple of days, sometimes it’s an illness that requires surgery. In our review, 10 diseases that not only slowly kill, but also terribly disfigure a person.
1. Necrosis of the jaw
Fortunately, this disease disappeared a long time ago. In the 1800s, workers in match factories were exposed to huge amounts of white phosphorus, a toxic substance that eventually led to terrible jaw pain. Eventually the entire jaw cavity would fill with pus and simply rot. At the same time, the jaw spread a miasma of decay and even glowed in the dark from an excess of phosphorus. If it was not removed surgically, the phosphorus would spread further to all organs of the body, leading to death.
2. Proteus syndrome
Proteus syndrome is one of the rarest diseases in the world. There are only about 200 cases reported worldwide. O This is a congenital disorder that causes excessive growth of various parts of the body. Asymmetrical growth of bones and skin often affects the skull and limbs, especially the legs. There is a theory that Joseph Merrick, the so-called "Elephant Man", suffers from Proteus syndrome, although DNA tests have not proven this.
3. Acromegaly
Acromegaly occurs when the pituitary gland produces excess growth hormone. As a rule, the pituitary gland is previously affected by a benign tumor. The development of the disease leads to the fact that victims begin to grow to completely disproportionate sizes. In addition to their enormous size, victims of acromegaly also have a prominent forehead and very sparsely set teeth. Probably the most famous person suffering from acromegaly was Andre the Giant, who grew to 220 centimeters and weighed more than 225 kg. If this disease is not treated in time, the body will grow to such a size that the heart cannot cope with the load, and the patient dies. Andre died of heart disease at the age of forty-six.
4. Leprosy
Leprosy is one of the most terrible diseases, which is caused by bacteria that destroy the skin. It manifests itself slowly: first, ulcers appear on the skin, which gradually expand until the patient begins to rot. The disease usually most severely affects the face, arms, legs and genitals. Although victims of leprosy do not lose entire limbs, victims often have their fingers, toes, and nose rot and fall off, leaving a nightmarish ragged hole in the middle of their face. Lepers have been cast out of society for centuries, and even today there are "leper colonies."
5. Smallpox
Another ancient disease is smallpox. It is even found on Egyptian mummies. It is believed that she was defeated in 1979. Two weeks after contracting the disease, the body becomes covered in a painful, bloody rash and pimples. After a few days, if the person manages to survive, the pimples dry out, leaving behind terrible scars. George Washington and Abraham Lincoln suffered from smallpox, as well as Joseph Stalin, who was especially embarrassed by smallpox on his face and ordered his photographs to be retouched.
6. Epidermodysplasia verruciformis
A very rare skin disease, epidermodysplasia verruciformis, is characterized by a person’s susceptibility to the papilloma virus, which causes rapid growth of scattered warts throughout the body. The world first heard about the terrible disease in 2007, when Dede Kosvar was diagnosed with the disease. Since then, the patient has undergone several operations, during which several kilograms of warts and papillomas were removed from him. Unfortunately, the disease progresses very quickly and Dede will require at least two surgeries a year to maintain a relatively normal appearance.
7. Porphyria
Porphyria disease is an inherited genetic disorder that results in the accumulation of porphyrins (organic compounds that have various functions in the body, including producing red blood cells). Porphyria primarily attacks the liver and can lead to all sorts of mental health problems. Sufferers of this skin condition should avoid exposure to sunlight, which causes swelling and blisters on the skin. It is believed that the appearance of people with porphyria gave rise to legends about vampires and werewolves.
8. Cutaneous leishmaniasis
9. Elephant disease
10. Necrotizing fasciitis
Minor cuts and abrasions are a part of everyone's life, and they usually cause minimal inconvenience. But if flesh-eating bacteria gets into the wound, even a small cut can become life-threatening in a matter of hours. The bacteria actually “eat” the flesh and release toxins that destroy the soft tissue. The only way to treat the infection is with massive amounts of antibiotics, but even then, all of the affected flesh must be cut out to stop the fasciitis from spreading. Surgeries also often involve amputation of limbs and other obvious mutilations. But even with medical attention, necrotizing fasciitis is fatal in 30-40% of all cases.
While scientists are looking for cures for terrible diseases, ordinary people can only get their fill.
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Today, science knows a number of very real ailments that even the greatest hypochondriacs and dreamers cannot invent.
In addition to the shocking symptoms, these diseases are also poorly studied. Their treatment is either impossible or ineffective, at least at this stage of medical development.
Morgellons disease
Everyone is familiar with the situation when “you get goosebumps on your skin.” Those with Morgellons disease describe their condition as follows: severe itching and an acute sensation that insects are crawling under the skin. The cause of the condition is not clear.
When looking at patients with this disease, one remembers scenes from horror films - people’s whole body itches, then abscesses appear, and from them begin to come out ... multi-colored threads and dark grains like sand. The wounds heal, leaving scars and scars, but soon appear in another place.
As a result of the tests, it turned out that what came out of the patients was not textile fibers, not hair, or even insects, but an unknown substance that originated in the body as a result of an unknown infection.
The threads were offered to forensic scientists for examination, and the substance was subjected to spectroscopic examination. But it was not one of the 800 fibers in the database. The result remained zero: the structure and composition of the thread did not match any of the 90 thousand organic substances!
Morgellons disease also has other symptoms: decreased mental capacity, chronic fatigue, depression, hair loss and muscle spasms.
Some doctors are inclined to believe that this is nothing more than a figment of the patients’ imagination. But what about multi-colored threads in this case? Others claim that Morgellons disease is a new type of biological weapon.
Cotard's syndrome
This is a rare condition where people think that they have either died or that some parts of their body have died. According to an article published in the Journal of Neuroscience, patients may believe that even their soul has died.
In 1880, the French neurologist Cotard first described this variant of delusion under the name delusion of denial. The syndrome was subsequently named after him. Some psychiatrists speak of Cotard's syndrome as a mirror image of manic delusions of grandeur.
A person suffering from this disease feels dead or non-existent. He feels that he has lost his vitality, blood and internal organs, and thinks that his insides are decomposing. This may be due to depression or severe mental retardation.
Delusions in Cotard syndrome are characterized by vivid, absurd and grotesquely exaggerated statements against a background of anxious affect. Characteristic complaints from patients are that, for example, the intestines have rotted, or that the patient is the greatest criminal in the history of mankind.
The structure of Cotard's syndrome is dominated by ideas of denial of the external world. Sometimes patients claim that they will face the most severe punishments for all the evil they have brought to humanity. Or that everything around died and the Earth was empty.
Ehlers-Danlos syndrome
This disease is characterized by the ability to bend limbs in directions impossible for normal people. People with Ehlers-Danlos syndrome also have hyperelastic skin. Half of the patients have genetic mutations.
The syndrome is one of the most common hereditary connective tissue diseases. It occurs with a frequency of 1 case per 100,000 newborns. The main symptom is a change in the properties of the skin, manifested in its increased extensibility and slight vulnerability. The skin of such people is thin and fragile. It can be raised by 2 centimeters in places where this is basically impossible in a healthy person. Even with minimal trauma to the skin, “lacerated” wounds occur that heal extremely slowly.
Urbach-Wiethe disease
An extremely rare genetic disease in which a person does not experience a sense of fear and does not perceive even sources of mortal danger as a threat. Scientists have proven that such a deviation is associated with almond-shaped structures in the brain. This discovery may be useful in the treatment of post-traumatic stress disorder. But doctors have not yet figured out how to make such “clinically fearless” people afraid.
Persistent sexual arousal syndrome
For people susceptible to this disease, orgasm brings more suffering than pleasure. The fact is that it happens to them often and, moreover, wherever and whenever. Interestingly, the syndrome was first diagnosed in 2001 and is observed predominantly in women. It is characterized by hypersensitivity, which is why the slightest external pressure can cause orgasm. The cause of the disease has not been established.
Stendhal syndrome
Another unusual disease in which a person experiences severe anxiety, trembling, hallucinations and dizziness when looking at... objects of art. Figuratively speaking, looking at a painting by Raphael, he may lose consciousness.
The syndrome was named after the 19th century French writer Stendhal, who described his feelings during a visit to Florence: “When I left the Church of the Holy Cross, my heart began to beat, I walked, afraid of collapsing to the ground...”
Similar symptoms can be caused not only by works of art, but also by the beauty of natural phenomena, animals, men and women. Treatment for Stendhal syndrome is not described, since the disorder is extremely rare and only near works of art and other beautiful phenomena, of which there are not so many around us. Therefore, the disease almost does not interfere with a full life. It remains unclear whether it is even worth treating the syndrome, which manifests itself in sensitive natures from an excess of beauty?
Progeria
A very rare genetic defect, which is characterized by a complex of changes in the skin and internal organs caused by premature aging of the body. The main forms are childhood progeria - Hutchinson-Gilford syndrome and adult progeria - Werner syndrome.
Progeria in adults is manifested by senile changes in the skin and skeletal muscles, the development of cataracts, and premature arteriosclerosis; It is observed most often in men aged 20-30 years.
Progeria childhood is characterized by proportional dwarfism, absence of subcutaneous tissue and recurrent pathological fractures.
Until the beginning of the 21st century, no special research was carried out on the causes of progeria; there was an opinion that no medications could cure this terrible disease. But science does not stand still. Now researchers are closely engaged in studying the causes that cause progeria.
"Stone Muscles"
55-year-old Englishman Robert Kinghorn suffers from a rare genetic disease in which the body forms a secondary skeleton and turns muscles into bones. Doctors call this disease progressive fibrodysplasia ossificans (POF).
To date, there are no methods for treating this disease, which affects about 2.5 thousand people in the world. In such patients, spontaneous growth of bone tissue occurs in the areas of the joints and muscles, as a result of which the person loses the ability to move and simply “turns to stone” - just like in the scary fairy tales that frightened us in childhood.
Robert received the terrible diagnosis when he was two years old. Then Kinghorn had to make a choice between standing or sitting for the rest of his life. He decided that standing was better, and since then he has never sat. Doctors predicted a quick death for the patient. But he turned out to be a man of strong character and is still alive.
Children who develop this condition are born normal, except for abnormal formation of the big toes. Over time, they develop tumors, which, changing location on the body, progressively paralyze the body. Doctors are currently searching for the POF gene. Its isolation may lead to the discovery of methods for treating “stone people.”
Alice in Wonderland syndrome
It turns out that this happens! With this neurological disorder, a person does not distinguish objects by size, considering everything to be tiny - micropsia, or huge - macropsia. Most often, this syndrome is provoked by taking hallucinogenic drugs or the presence of a tumor in the brain.
The disease was first noted by Dr. Lippman in 1952.
People with Alice in Wonderland syndrome see things that are completely different from what they really are. For example, the doorknob may seem to them as big as the door itself, the floor may seem vertical, and the walls of the room will come closer to each other and practically connect. In their minds, chairs and tables can fly through the air and even waltz. Often such people see objects much smaller than they actually are. Visual perception changes so much that a person completely loses control over reality.
As in Lewis Carroll’s fairy tale “Alice in Wonderland,” patients do not understand what is really happening and what they only imagine. There is even a hypothesis: the author of the book suffered from migraines, before the attack of which he began to experience micropsia.
There are quite a few causes of micropsia: migraine, epilepsy, schizophrenia, fever. The syndrome also occurs when taking hallucinogenic drugs, LSD, and sometimes under the influence of marijuana.
Alien hand syndrome
The disease, also called “anarchist hand,” is a neuropsychiatric disorder consisting of impaired ability to make purposeful movements. With it, one or even both hands act “on their own,” regardless of the will of the owner. Sometimes this is accompanied by attacks of epilepsy. Another name for the syndrome is Dr. Strangelove's disease, in honor of the hero of the film "Dr. Strangelove" who suffered from it, whose hand spontaneously raised itself in a Nazi salute.
In 1998, a journal devoted to neurosurgery published the story of a woman whose left hand... involuntarily strangled her and hit her in the face!
If the hand makes chaotic movements, hits its owner or pinches, this is not so bad. Sometimes she starts arguing with the owner - for example, the “good” one ties a shoelace, and the “evil” one unties it.
Some argue that the “anarchist hand” acts under the influence of the unconscious, as if showing a person’s deep attitude towards certain things or actions. Psychiatrists explain this syndrome by disturbances in the interaction between the hemispheres of the brain.
In this article we will tell our readers about very rare diseases that nevertheless exist and may even have had an impact on some aspects.
Stendhal syndrome
A person suffering from this disease, finding himself in a place where there are a lot of works of art, begins to experience excitement, increased heart rate and even hallucinations. For people who have this syndrome, the Uffizi Gallery in Florence is considered the most dangerous place.
It was on the basis of the symptoms experienced by tourists visiting this gallery that this disease was described. The syndrome got its name due to the fact that it was described by Stendhal in his book “Naples and Florence: a journey from Milan to Reggio” back in 1817, but despite the large amount of evidence, this syndrome was officially documented only in 1979 by the Italian psychiatrist Magherini. He studied more than a hundred identical cases of this disease. The first such diagnosis was made in 1982.
People with this disease hear various noises in their heads and even explosions. Most often, the syndrome manifests itself a couple of hours before falling asleep or almost immediately after it. Patients with this disease complain of anxiety, which is accompanied by an increased heart rate. It happens that the syndrome is accompanied by flashes of bright light in the head. Everything would be fine, but all these sensations are quite painful, and some even feel like they are having a stroke.
Some characterize the attack by the sound of string instruments, while for others the sound is more like a bomb explosion. Doctors' assumptions boil down to the fact that such sleep disturbances may be associated with overexertion and stress. Most patients are women. There have been cases of symptoms of this disease in people under 10 years of age, but the average age of most patients is 58 years.
In the medical community, this syndrome is not classified as either auditory hallucinations or epilepsy, but there is no description of this syndrome in textbooks, which is due not so much to its rarity as to the low degree of knowledge.
There is no effective treatment yet, but some improvements in the condition of patients are observed with the use of clomipramine and clonazepam. In addition, patients are advised to spend more time in the fresh air, carefully monitor their daily routine and exercise. All this helps relieve stress and prevent symptoms of the disease.
Capgras' fallacy
People with this disease believe that someone close to them, most often a husband or wife, has been replaced by a clone. As a result, the patient tries in every possible way to avoid the “imposter” and does not want to sleep in the same bed with him.
Doctors believe that this disease may be the result of a brain injury or an overdose of drugs. It is also widely believed that the Capgras delusion is caused by lesions in the right hemisphere of the cerebral cortex.
A typical example of Blaschko lines
Some people may see stripes all over their body. They were called the Blaschko line, in honor of the German dermatologist Alfred Blaschko. The doctor discovered this phenomenon in 1901.
Apparently, this pattern is genetically determined and embedded in the DNA, like many inherited diseases of the skin and mucous membranes. Such stripes appear in the first months of life.
Micropsia or Alice in Wonderland syndrome
This neurological disorder impairs visual perception. People and animals seem smaller to the patient than they are, and the distances between objects become distorted. This disease is often called “Lilliputian vision” or “dwarf hallucinations.”
Micropsia affects not only vision, but also touch and hearing. Even his own body may appear different to the patient. Doctors believe that this disease is associated with migraines. In addition, micropsia can be caused by epilepsy or due to exposure to drugs. This distortion of perception is also observed in children 5-10 years old and appears quite often with the onset of darkness, when the brain lacks information about the size of surrounding objects.
Blue skin syndrome
Most patients never master speech, even after reaching adulthood, or only learn a few simple words. However, they understand much more than they can say or express. The name “happy puppet” comes from the characteristic walking of such patients on “stiff legs” and frequent causeless laughter.
Erythropoietic porphyria or Gunther's disease
A person with erythropoietic porphyria
A very rare disease. There are about 200 patients in the world. Caused by a genetic defect. The skin of patients has very high photosensitivity. From the light, the patient's skin begins to itch very much and becomes covered with ulcers and blisters.
Ulcers and inflammation affect the ears, nose and cartilage and they are significantly deformed. The eyelids also become covered with ulcers. A person gradually turns into a living mummy. The appearance of such a person is reminiscent of images in medieval grimoires; in addition, his teeth are colored brownish-red due to porphyrin deposits in the enamel, and when exposed to ultraviolet radiation they glow purple-red.
It may very well be that it was Gunther’s disease and people suffering from it that formed ideas about creatures that are afraid of daylight and drink human blood - vampires.
Robin syndrome
Child with Robin syndrome
A child born with this syndrome is not able to eat and breathe normally because he has an underdeveloped lower jaw. In addition, his palate has clefts, and his tongue is sunken. Sometimes the lower jaw may be completely absent, causing the face to take on bird-like features. The disease is treated with plastic surgery.
CIPA
Gabby Gigras is an energetic child who looks no different from her peers, but the girl is different from most people in that she suffers from a very rare disease known as CIPA.
Gabby has a congenital insensitivity to pain, which is accompanied by anhidrosis (lack of sweating). There are only 100 documented cases of this disease worldwide.
Gabby was born without the ability to sense cold, pain or heat. To many, such properties of the body may seem very useful, but in reality this is not the case. Pain and temperature sensations perform a very important protective function.
For example, if you accidentally find yourself near an open fire, you will immediately try to move to a safe distance, getting away with a minor burn at worst, and all this will happen at the reflex level, and a person like Gabi may lose a limb before he notices what is happening something wrong.
The girl's parents noticed that something was wrong when they discovered that the 5-month-old child had bitten his fingers until they bled. Gabby later lost an eye and suffered serious injuries as the pain continued to scratch her wounds and sustain various household injuries. The parents are doing everything possible so that the girl can live a normal life.
Cystinosis
Cystinosis is a condition where cystine crystals appear in the body. Lily Sutcliffe, who suffers from this rare hereditary disease, is forced to take a cocktail of drugs every day to avoid petrification. There are about 2,000 people in the world who have this disease.
Syndrome
Shiloh Pepin was born with fused legs. This disease is often called a syndrome. Doctors believed that the girl would live only a few days, but she lived for ten years. Shiloh Pepin died on 10/23/08. In the photo she is sitting on a table in Kennebunkropt, Maine (USA) 2007.
Shiloh Pepin was born with fused legs, a condition often called “mermaid syndrome.” Although doctors believed that the girl was destined to live only a few days, she lived for ten years. Shiloh died on October 23, 2008. She is pictured here sitting on a table in her home in Kennebunkropt, Maine in 2007.
Fatal familial insomnia
Rare genetic disorder. Patients with FSB constantly want to fall asleep, but cannot. Due to a long lack of sleep, patients go crazy and die painfully, despite the fact that the last few months before pass in a twilight state of consciousness.
The disease is called familial because it affects entire families. In total, there are about 40 families with this disease in the world. Sherrill Dinges, 29, is a member of one such family. All of her relatives are carriers of the FFB gene. She refuses the test. The FSB has already killed her mother, her grandfather and her uncle. Her sister did not inherit the fatal gene, and she herself refuses to be tested.
FSB begins with mild cramps, increased anxiety and insomnia. Due to a long lack of sleep, patients eventually begin to hallucinate and become clouded, and after a few months they die.
In this article we will tell our readers about very rare diseases that nevertheless exist and may even have had an impact on some historical and mythological moments. Stendhal syndrome A person suffering from this disease, when entering a place where there are a lot of works of art, begins to experience excitement, increased heart rate and even hallucinations. For people who...
Culture
More and more often these days you can hear about new diseases that were previously scary to even imagine.
These terrifying illnesses of very dubious origin frighten us and make us thank our fate for the fact that most of us only suffered from the flu and sore throat.
There are dozens, hundreds of different exotic diseases that not only kill a person, but slowly cripple him. Here is a list of the most terrible diseases that pose a serious danger to people.
1. Necrosis of the jaw
Fortunately, this disease disappeared many years ago.
What is known about it is that in the early 19th century, match industry workers were exposed to huge amounts of white phosphorus, a highly toxic substance that ultimately caused terrible jaw pain.
After some time, the jaw cavity filled with pus and simply rotted. From the huge amount of phosphorus that the body received, the jaw even glowed in the dark.
If the bone was not surgically removed, phosphorus continued to destroy the body, eventually leading to the death of the patient.
2.Acromegaly disease
This disease occurs when the pituitary gland produces too much growth hormone. As a rule, this disease occurs in victims of benign tumors.
Acromegaly is characterized not only by enormous height, but also by a bulging forehead, as well as a large gap between the teeth.
The most famous case of this disease was identified in Andre the Giant. As a result of this disease, his height reached 2.2 meters.
The poor man's weight was 225 kg. If acromegaly is not treated in time, the heart cannot withstand such heavy loads associated with increased body growth. Andre the Giant died of heart disease at the age of 46.
3. Patients with leprosy
Leprosy is perhaps one of the most terrible diseases known to medicine. The disease is caused by a special bacterium that destroys the skin.
A person with leprosy literally begins to rot alive. Typically, the disease primarily affects the face, arms, legs and genitals of a person.
Although the poor fellow does not lose all his limbs, the disease often takes away the leper's fingers and toes, and also destroys part of his face. Very often the nose is affected, resulting in a terrible face, and a shocking ragged hole in the place of the nose.
The attitude towards lepers is also terrible. At all times, people with such a disease were shunned; they were exiles from any society. And even in the modern world there are entire settlements of lepers.
4. Smallpox disease
After contracting smallpox, the body becomes covered in a rash in the form of painful pimples. The disease is terrible because it leaves behind huge scars. Therefore, even if you manage to survive from this disease, the consequences are quite sad: scars remain all over your body.
Smallpox appeared a very long time ago. Experts have proven that even in ancient Egypt, people suffered from this disease. This is also evidenced by the mummies found by archaeologists.
It is known that at one time such famous personalities as George Washington, Abraham Lincoln, and Joseph Stalin suffered from smallpox.
In the case of the Soviet leader, the disease was especially acute, leaving behind obvious consequences on the face. Stalin was embarrassed by the scars on his face and always asked to retouch the photographs in which he was depicted.
5. Porphyria disease
Porphyria is a genetic disorder that results in the accumulation of porphyrins (organic compounds that have various functions in the body; they also produce red blood cells).
The disease affects the entire body, primarily affecting the liver. This disease is also dangerous for the human psyche.
People suffering from this skin condition should limit themselves from sun exposure, which can aggravate their overall health. It is believed that it was the existence of porphyria patients that gave rise to legends about vampires and werewolves.
6. Cutaneous leishmaniasis
And soon the tiny and harmless bite turns into an ugly, purulent ulcer. Therefore, bites to the face are especially dangerous. It takes a long time for the wounds to heal.
Without proper treatment, a person may die. Many people in Afghanistan suffer from this disease.
7. Elephant disease
The disease is common in tropical areas of Africa, and more than one hundred million people suffer from elephantiasis. Victims of this disease experience frequent headaches and nausea.
The most effective means of combating the disease are special antibiotics. In the worst and most advanced cases, the patient cannot avoid surgical intervention.
8. Necrotizing fasciitis
Minor cuts and abrasions are a part of our lives. And they're pretty harmless as long as there aren't flesh-eating bacteria nearby. Then in a matter of seconds a small wound can become life-threatening.
Bacteria eat away living flesh, and only amputation of some tissues can stop the spread of the disease. The patient is treated with antibiotics. However, even despite intensive treatment, 30-40 percent of all cases of the disease are fatal.
Viral dermatoses, acrodynia (morbus feer)
Acrodynia, being, in all likelihood, an infectious disease, is expressed by a special dysfunction of the autonomic nervous system, mental disorder, dystrophies, edema, various skin phenomena, impaired sensitivity, pain, etc.
There are descriptions of epidemics of the disease in cold and cool seasons in children aged from 1 - 2 months to 13 - 14 years.
The initial manifestations of acrodynia are: fatigue, low-grade fever, respiratory catarrh, depression, apathy, lack of concentration and attention. Sometimes there are more severe mental disorders - delirium, anxiety, hallucinations, insomnia, etc.
Pain in the limbs, sensory disturbances, increased sweating, feeling of heat, muscle hypotension appear; it is difficult for the patient to move, he lies motionless in bed.
"Synthetic dermatology"
Lyuben Popov
With superficial candidiasis of the mucous membranes and skin, fungi are located in the stratum corneum in the form of mycelium and spores, singly or in groups in the form of clusters, rarely in the form of drusen. The mycelium is composed of individual thin short fibers, round spores up to 5 cm in size, with a clearly defined capsule, Gram stained purple. In cases of deep monoliasis...
The causative agent is Achorion guinckeanum. Through close contact with cats, dogs, mice and rats, animal scab is transmitted to humans, which is expressed by the appearance of scales and crusts, most often on smooth skin. Animals can transmit microsporia to humans, especially children. Its causative agents are Microsporon gypseum, Microsp. felineum, Microsp. lanosum, etc. Special and rare clinical forms of trichophytosis are alopecia…
The causative agent of this disease, Trichosporon cutaneum BeurmannGougerot-Ota (1909 - 1926), affects the superficial layers of the beard and mustache. Nodular, enveloping layers form on the hair, in which fungal spores 3-4 r long can be found. In tropical and subtropical countries, other types of trichosporon have been found on the hair of men and women. Black piedra (piedra nigra)…
This toenail lesion is caused by Scopulariopsis brevicaulis var. hominis Brumpt; s. Penicillium brevicaule (1910). Lesions often involve the nails of the big toes, sparing the skin between the toes. In very rare cases, the nails of other fingers may be affected. The nail plate is affected, becoming dark or black, rough, cracked, and brittle. You can easily separate a piece from it...
Due to the purely saprophytic nature of these fungi and their poor adaptation in humans, the infections they cause are very rare, and it is very difficult to prove their pathological role. Aspergillosis. Epidermomycosis, onychomycosis, stomatitis, pharyngitis and otomycosis are rarely observed. Aspergillosis of torpid ulcers is known. Visceral aspergillosis, pulmonary aspergillosis, meningitis and brain abscesses are more severe and serious diseases. With maduromycosis in some...
Hormodendrosis. Like cladosporiosis, the causative agents of this disease are dark-colored fungi belonging to the genus Dematiaceae. Species pathogenic to the skin: Hormodendron pendrosoi, Horm. compactum, Horm. Japonicum, Phialophora verrucosa, Horm. rossicum, Meriina, causing chromoblastomycosis (see). Horm. fontoynonti Langeron (1913) is the causative agent of Achromia tropica s. Tinea flava. Skin diseases caused by hormodendrons are rare in temperate zones. Diseases caused by representatives...
European blastomycosis or cryptococcosis is a chronic systemic disease with spontaneous remissions, affecting mainly the membranes of the brain, lungs, and skin. It is called Cgurtococcus neoformans Vuillemin (Torulopsis neoformans, Cryptococcus meningitidis, Torula hystolytica). Clinically, the disease occurs in the form of meningeal syndrome, as well as in the pulmonary form, but other organs can also be affected. The skin is affected in 10% of cases. Possible combination with malignant...
Caused by Blastomyces dermatitides. Most often, skin changes occur in the form of chronic granulomatous, purulent, vegetative processes. This form of blastomycosis can also develop in various internal organs (lungs, intestines, etc.), in the nervous system, in joints and bones. Histologically, this is a deep granulomatous process, expressed by papilomatosis, acanthosis, intraepidermal and dermal abscesses, giant and epithelioid cells, lymphoid and plasma cells, leukocytes...
